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Quest Vitamins LTD,
8 Venture Way,
Aston Science Park,
B7 4AP.

Tel: 0121 359 0056
Fax: 0121 359 0313
Registered in England No. 2530437



Creatine, a naturally occurring substance, has an important role in the production of energy in humans. It a supplement of choice as a performance enhancer. It is thought that supplemental creatine can build up a reserve of phosphocreatine in the muscles as well as expedite the manufacture by the body of phosphocreatine when it has been used up during athletic performance.


Creatine is used by the body in the energy cycle, combining with Phosphorus to recycle adenosine di-phosphate (ADP) as adenosine tri-phosphate (ATP). 95% is stored within the muscle cells.


Building muscularity:
Creatine is used by bodybuilders in the form of creatine monohydrate to:

  • Delay the onset of fatigue
  • Improve energy for muscular work
  • Increase muscular strength (1)
  • Enhance muscular recovery
  • Improve muscle tone


Muscular Fatigue:
Conditions involving muscular Fatigue may benefit from creatine supplementation.

Lipid Levels:
Creatine has shown to effectively lower lipid levels.


Some formulations can lead to gastrointestinal upsets and the long-term safety has not been determined.
As with all supplements taken in high doses, high-quality forms of creatine should be chosen carefully. Even low concentrations of contaminants may be harmful.

Individuals with kidney disease should avoid creatine, especially if undergoing dialysis.


Caffeine appears to block the effect of creatine (3).


1. Earnest CP et al: The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol Scand 1995 Feb; 153(2):207-9.
2. Febbraio MA et al: Effect of creatine supplementation on intramuscular TCr, metabolism and performance during intermittent, supramaximal exercise in humans. Acta Physiol Scand 1995 Dec; 155(4): 387-95.
3. Williams MH, et al. Creatine supplementation and exercise performance: An update. J Am Coll Nutr 17: 216-234, 1998.